Calcium & Vitamin K
Role
The calcium supplementation story is one of the most instructive examples of nutrition science's tendency to identify a single nutrient deficiency and recommend supplementation without understanding the broader nutrient interaction context — producing the paradox of calcium supplements associated with increased cardiovascular risk (arterial calcification) in women who lack adequate vitamin K2 to direct the calcium to bone. The majority of people supplementing calcium for bone health have never been told about vitamin K2, creating a situation where the supplement intended to protect their bones may be calcifying their arteries. Understanding the calcium-D-K2 system rather than calcium alone represents the difference between educated supplementation and potentially harmful nutritional over-simplification.